The latest information suggests that women with the absence of certain genes are more susceptible to reduced success in achieving conception. The cause of infertility is attributed to cervical problems, hormonal imbalance, and uterine malformation. Scientific journals report that the problem may be accentuated due to the absence of certain genes. Maternal factors present in the coding are crucial for the development of the preimplantation embryo. NLRP 2 was first described in the year 2000. Albeit limited knowledge prevails about maternal effect genes that play important role in embryonic development.
The gene described as NlRP 2 if absent was responsible for many negative aspects. This is a maternal effect gene that plays an important role during embryogenesis the absence of which was related to repeatedly failed pregnancies, embryonic anomalies, malformation of reproductive organs, and complete infertility. In some cases, babies were born with disabilities. All this was tested on lab mice but the outcome on humans is evident.
This finding furthers the scope of in-vitro fertilization where the egg is fertilised in the dish and then placed into the uterus.