Friday, March 31, 2017

Male Infertility & Treatment

In earlier times the inability to bear a child was squarely blamed on woman. With all the associated dogmas that are attributed to a woman unable to bear a child life became miserable for the unfortunate.  

The failure of conception to take place can be due to an infertile male as well. Hence after proper tests and diagnostics it is determine who needs corrective treatment. With advance therapies available conception is possible.    

Males become infertile due to lack of proper amount of sperms. The sperms could also be deformed and have no motility to fertilise the egg. Blockages is the reproductive apparatus can also hinder fertilisation of egg.  The problems could be hormonal, genetic and autoimmune,  There are many underlying medical inadequacies that require a look into through tests before corrective action can be taken.

Usually the treatment is improvement in lifestyle as well as usage of assisted conception techniques. Chronic alcoholism and tobacco use are responsible for low sperm count. The modified IVF treatment used are GIFT & ZIFT. The former is gamete intrafallopian transfer and zygote intrafallopian transfer. these are modified versions of IVF. These procedures are closer to natural conception. But the procedures require invasive interventions hence IVF procedure is preferred treatment all over.   

Thursday, March 23, 2017

Latest About Women and Infertility


The latest information suggests that women with the absence of certain genes are more susceptible to reduced success in achieving conception.  The cause of infertility is attributed to cervical problems, hormonal imbalance, and uterine malformation.   Scientific journals report that the problem may be accentuated due to the absence of certain genes. Maternal factors present in the coding are crucial for the development of the preimplantation embryo. NLRP 2 was first described in the year 2000. Albeit limited knowledge prevails about maternal effect genes that play important role in embryonic development.   

The gene described as NlRP 2 if absent was responsible for many negative aspects. This is a maternal effect gene that plays an important role during embryogenesis the absence of which was related to repeatedly failed pregnancies, embryonic anomalies, malformation of reproductive organs, and complete infertility. In some cases, babies were born with disabilities. All this was tested on lab mice but the outcome on humans is evident.

This finding furthers the scope of in-vitro fertilization where the egg is fertilised in the dish and then placed into the uterus.